Conformational flexibility and binding interactions of the G protein βγ heterodimer
نویسندگان
چکیده
منابع مشابه
Flexibility and conformational entropy in protein-protein binding.
To better understand the interplay between protein-protein binding and protein dynamics, we analyzed molecular dynamics simulations of 17 protein-protein complexes and their unbound components. Complex formation does not restrict the conformational freedom of the partner proteins as a whole, but, rather, it leads to a redistribution of dynamics. We calculate the change in conformational entropy...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2010
ISSN: 0887-3585
DOI: 10.1002/prot.22899